Pathway-27 Consortium

 

PATHWAY-27 includes 25 partners broadly distributed in Europe: west to east, south to north Europe, including one Candidate Country (Turkey). The EU Consortium consists of different organisation types, namely: Universities, Research Institutes and SMEs.

Partners in France

APPLICATIONS SANTE DES LIPIDES (ASL)

 

Applications Santé des Lipides (ASL) is a start up co-funded in 2005 by Gérard PIERONI former director of research at the CNRS (French National Center for Scientific Research). ASL activity is focused on the production  and marketing of egg lipid products specifically enriched in DHA for the agro food and complement markets as  well as for drug industry.

ASL is a supplier of egg products enriched in omega 3 fatty acids with a high ratio of DHA versus EPA (>10) and DHA versus α-linolenic acid (≈10). ASL products have been tested in animal studies and in clinical trials on elderly, sportsman and diabetic. The use of these products in respiratory insufficiency is patented. Purified egg phospholipids from ASL, GPL-DHA® 8, have obtained the EC status of "Novel Food" (2010).

Scientific responsible: GAD, M.H., Ph.D. (mh.gad@asl-lipides.com)

Website: http://www.asl-lipides.com/

Project partner(s):

INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA)


INRA is a public French research organisation and has among its strategic interests the impact of food on human health and well-being. It is ranked 2nd in the world and 1st in Europe for publications in agricultural sciences, and plant and animal sciences.
Two different Joint Research Units (UNH and STLO) will be involved in PATHWAY-27. The Unit of Human Nutrition (UNH) has as goal the elucidation of key mechanisms involved in the prevention of ageing-associated diseases by nutrients and foods- Increasing our understanding of the needs is crucial for establishing nutritional recommendations and preventing metabolic alterations. To address this issue, UNH is developing an innovative approach integrating the human complexity at the physiological, metabolic and nutritional levels. The UNH scientific excellence is based on strong competencies in human nutrition, physiology, biochemistry, metabolism, cell and molecular biology. The unit will be contributing to WP5 and leading the Task 5.2. "Selection and characterization of volunteers and Ethic Committee approval". In clinical studies, the Unit has a strong integration within the Centre of Research in Human Nutrition (CRNH) for the management of the nutritional interventions The Research Unit on Science & Technology of Milk and Egg (STLO) in Rennes is the largest research unit at INRA involved on milk and egg science and technology and publishes around 60 peer-reviewed article on these topics every year. It is world-wide known for its membrane separation projects linked to milk molecules fractionation. STLO is a pillar of CEREL (http://www.cerel.org), the European Centre for Dairy Research and Training. STLO is also in the core of VALORIAL, a network associating more than 200 agri-food companies and research institutes and aiming at promoting research and innovation in food products. A 800 m² Dairy Platform is part of the STLO and provides a unique experimental facility dedicated to conducting research on milk and dairy products. The Dairy Platform is certified to ISO 9001:2008 for Quality Management System. It provides a complete range of dairy technologies and allows the design of dairy products in perfectly-controlled conditions. STLO has also developed an in vitro dynamic digestion model. In PATHWAY-27, STLO will be the leader of WP2 and in charge of Task 6.1 in WP6.

Scientific responsible: Didier Dupont  (Didier.Dupont@rennes.inra.fr)

Website: http://www.inra.fr/

Project partner(s):

CENTRE DE RECHERCHE EN NUTRITION HUMAINE AUVERGNE CRNH AUVERGNE (CRNH)

 

The CRNH Auvergne brings together 6 research units including 17 research teams and a Nutrition Investigation Platform (NIP) dedicated to interventional studies in volunteers. CRNH Auvergne research area is the prevention of physiological dysfunctions in elderly and of chronic diseases. CRNH Auvergne is one of the world leading centres for protein and polyphenol metabolism. Research is oriented towards the prevention of sarcopenia, osteoporosis, degenerative cardiovascular diseases, gut microflora, digestive pain and hormone dependent cancers. The NIP surface is approximately 400 m2. It contains 7 beds for one-day investigations, including 2 beds for the more invasive ones. NIP staff includes 2 nurses, 2 dieticians, 2 clinical research assistants, 1 cooker, one secretary, and 3 MDs. The NIP makes it possible to explore body composition (BIA, DEXA, CT-scan, MRI), energy metabolism, protein metabolism using whole-body and regional tracer kinetics, insulin sensitivity, non-energy nutrient effects. This NIP is remarkable by the presence of an experimental kitchen and two calorimetric chambers.

Scientific responsible: Noel J Cano (noel.cano@clermont.inra.fr)

Website: http://www1.clermont.inra.fr/crnh/

Project partner(s):